Pepper S. Schedin

This study identifies SOX9 and SEMA7A as regulators of cell plasticity in postpartum mammary glands and links their dysregulation to breast cancer progression and metastasis.

This study identifies immune mimicry in breast cancer cells, where neoplastic cells express leukocyte receptors, enhancing tumor aggressiveness and therapy resistance.

This study identifies SNO-COX-2 as a biomarker for mesenchymal phenotypes in breast cancer, showing its microenvironmental regulation and association with invasive growth.

This study examines liver transcriptional changes during lactation and weaning in mice, finding similarities between liver involution and pre-metastatic niches, with implications for breast cancer metastasis.

This study shows that metformin reduces breast cancer in rats during early postmenopause but discontinuation harms metabolic health, linking timing of treatment to cancer and metabolic outcomes.

This study shows that vitamin D's anti-cancer effects are reduced in post-wean mice due to altered liver metabolism, highlighting the importance of reproductive history in treatment efficacy.

Scissor identifies cell subpopulations from single-cell data correlated with specific phenotypes using clinical information, revealing biologically relevant subpopulations in lung and melanoma cancers.