Author

Amanda J. Clark

The University of Texas Southwestern Medical CenterORCID 0000-0002-6550-730XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Afaf SalibaiD· 1 shared Alejandra L Lorenzen· 1 shared Anders Hayden BergiD· 1 shared Esmeralda Trevino· 1 shared Guanshi ZhangiD· 1 shared Jason C. O’ConnoriD· 1 shared Kumar SharmaiD· 1 shared Kyle Q. VuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPathology

Afaf SalibaORCID

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1 paper

Recent·Most cited

Quinolinic acid metabolism may mitigate AKI to CKD transition

Marie Christelle Saadé, Afaf Saliba, Amanda J. Clark, Subrata Debnath, Shiqi Zhang, Nagarjunachary Ragi, Valerie Etzrodt, Rahil Alhumaidi, Kyle Q. Vu, Tao Yu, Esmeralda Trevino, Alejandra L Lorenzen, Guanshi Zhang, Anders Hayden Berg, Jason C. O’Connor, , Kumar Sharma

This study identifies quinolinic acid as a mediator of kidney injury and fibrosis, suggesting it as a potential therapeutic target for preventing AKI-to-CKD progression.

bioRxiv · Oct 10, 2025 · PreprintPathology