Author

Johnny Debebe

Imperial College LondonORCID 0000-0002-6551-5641Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Alexander PayneiD· 1 shared Becca AsquithiD· 1 shared Charandeep Kaur· 1 shared Christoph Niederalt· 1 shared David A. PriceiD· 1 shared Florence Susan WongiD· 1 shared James A. TraherneiD· 1 shared John TrowsdaleiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Alexander PayneORCID

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2 papers

Recent·Most cited

Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes

Laura Mora-Bitria, Johnny Debebe, Kelly L. Miners, Kristin Ladell, Charandeep Kaur, James A. Traherne, Wei Jiang, David A. Price, Linda Hadcocks, Nicholas A. R. McQuibban, John Trowsdale, Florence Susan Wong, Nikolas Pontikos, Christoph Niederalt, Becca Asquith

The paper investigates how inhibitory KIRs modify HLA class II protective associations in Type 1 Diabetes, finding that iKIRs reduce HLA class II-mediated protection.

PLoS Genetics · Dec 26, 2024Peer-reviewedImmunology

Nanopore adaptive sequencing for mixed samples, whole exome capture and targeted panels.

Alexander Payne, Nadine Holmes, Thomas Clarke, Rory Munro, Johnny Debebe, Matthew Loose

The paper introduces a method for targeted sequencing using nanopore adaptive sequencing, enabling efficient enrichment of specific genes and chromosomes from mixed samples.

Nature Biotechnology · Nov 30, 2020Peer-reviewedGenomics