Alexander Payne

Icarust simulates Oxford Nanopore sequencing runs to enable realistic testing of adaptive sampling software without using real sequencing consumables.

The paper shows that NANOG and NODAL interact with DPY30 to regulate H3K4me3 deposition in axolotl primitive ectoderm, conserved in humans, establishing a basal state of vertebrate pluripotency.

The paper introduces a barcode-aware adaptive sampling tool for nanopore sequencers, enabling targeted analysis of multiple genomes on a single flow cell.

MinoTour provides a LIMS system for real-time monitoring and analysis of Oxford Nanopore sequencers, enabling automated analysis during sequencing runs.

The paper demonstrates how real-time nanopore sequencing with minoTour can accelerate SARS-CoV-2 consensus generation and lineage assignment by predicting optimal sequencing completion points.

The paper introduces a method for targeted sequencing using nanopore adaptive sequencing, enabling efficient enrichment of specific genes and chromosomes from mixed samples.

The paper uses nanopore sequencing to analyze poly(A) RNA from human cells, identifying long transcripts and modifications not captured by traditional methods.

BulkVis visualizes Oxford Nanopore bulk fast5 files to inspect signal data and identify incorrectly split long reads.