Caroline Dean

This study uses pPOINT-seq to analyze co-transcriptional splicing in Arabidopsis, finding that cold exposure globally enhances splicing and alters intron processing patterns.

The paper investigates cold-induced repression of FLC in Arabidopsis, finding distinct mechanisms involving splicing changes and reduced transcription initiation, separate from warm-induced repression.

SlimVar enables in vivo single-molecule tracking of chromatin regulators in Arabidopsis thaliana root cells, revealing dynamic protein assemblies during FLC silencing.

This study investigates the role of VIN3 and VRN5 VEL polymerization domains in cold-induced epigenetic silencing of FLC in Arabidopsis, showing distinct functional contributions.

The paper shows cold-induced changes in nucleosome dynamics at the FLC locus in Arabidopsis, leading to transcriptional repression through chromatin structure transitions.

This study shows that local adaptation in Arabidopsis thaliana involves strong and variable selection on multiple traits, with trade-offs and life-history strategies affecting fitness.

The paper develops a computational model to explain how proximal termination influences the rate of Polycomb silencing establishment at the FLC locus in Arabidopsis.

This paper shows how transcription termination via the CPF-like phosphatase module affects chromatin silencing of FLC in Arabidopsis, influencing flowering time.

This study investigates the in vivo properties of Arabidopsis FCA condensates involved in RNA 3' processing, revealing their modular structure and interactions with FLL2 and RNA.

The paper shows that antisense transcription and PRC2 silencing work together to regulate FLC during vernalization, with different response dynamics influenced by temperature and growth conditions.

The paper shows that FLC gene expression in Arabidopsis is regulated by both analog and digital modes before cold exposure, with analog preceding digital and leading to gradual repression.

This study shows VAL1 coordinates co-transcriptional repression and chromatin regulation at Arabidopsis FLC by assembling co-repressors and regulating H2Aub and H3K27me3 marks.

The paper shows that natural variation in FLC levels and early silencing, not epigenetic silencing, determines vernalization response in Arabidopsis to different climates.