Author

Andrew J. Butcko

Henry Ford HealthORCID 0000-0002-6559-8053Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Emilio P. MottilloiD· 2 shared Grace Teskey· 2 shared James G G GrannemaniD· 2 shared Nivedita TiwariiD· 2 shared Abir A. RahmaniD· 1 shared Amit KumariD· 1 shared Anuradha YadaviD· 1 shared Christopher V. KellyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPhysiology

Emilio P. MottilloORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PNPLA3 I148M Reduces Hepatic Triacylglycerol Secretion and Mitigates Left Ventricular Diastolic Dysfunction in MASH Diet Mice

Andrew J. Butcko, Parsa Kamali, Nivedita Tiwari, Abir A. Rahman, Grace Teskey, Kehinde Ahmad Adeshina, Nikhlesh Kumar Singh, James G. Granneman, Emilio P. Mottillo

This study shows that PNPLA3-I148M reduces hepatic TAG secretion and protects against cardiac diastolic dysfunction in MASH diet mice, despite promoting liver steatosis.

bioRxiv · Apr 24, 2025 · PreprintPhysiology

Lipid Droplet Targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis

Grace Teskey, Nivedita Tiwari, Andrew J. Butcko, Amit Kumar, Anuradha Yadav, Yu‐ming M. Huang, Christopher V. Kelly, James G G Granneman, James W. Perfield, Emilio P. Mottillo

This study shows that LD targeting of ABHD5 and PNPLA3 I148M is necessary for their interaction and promotes liver steatosis.

Journal of Biological Chemistry · Jan 13, 2025Peer-reviewedCell Biology