Author

W. Todd Miller

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-6566-0064Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Agnes J. VialeiD· 1 shared Ahmed I. MarwaniD· 1 shared Aida M. S. SalemiD· 1 shared Alan R. ShuldineriD· 1 shared Allison E. Ashley‐KochiD· 1 shared Ann Baako· 1 shared Anna AlkelaiiD· 1 shared Anna Yurrita· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Agnes J. VialeORCID

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2 papers

Recent·Most cited

The contribution of de novo coding mutations to meningomyelocele

Yoo-Jin Jiny Ha, Ashna Nisal, Isaac Tang, Chanjae Lee, Ishani Jhamb, Cassidy Wallace, Robyn E. Howarth, Sarah Schroeder, Keng Ioi Vong, Naomi Meave Ojeda, Fiza Jiwani, Chelsea Barrows, Sangmoon Lee, Nan Jiang, Arzoo M. Patel, , Joseph G. Gleeson

The paper identifies de novo mutations contributing to meningomyelocele risk by analyzing trios and finding damaging mutations in 22.3% of cases.

Nature · Mar 26, 2025Peer-reviewedGenetic & Genomic Medicine

A microglia clonal inflammatory disorder in Alzheimer's Disease

Rocío Vicario, Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y. Hayashi, Barbara P. Craddock, Nicholas D. Socci, Araitz Alberdi, Ann Baako, Oyku Ay, Masato Ogishi, Estibaliz Lopez-Rodrigo, Rajya L. Kappagantula, Agnes J. Viale, , Frédéric Geissmann

The paper identifies microglia-specific somatic clones with pathogenic variants in Alzheimer's Disease patients that drive neuro-inflammation through the MAPK pathway.

eLife · Jan 29, 2025Peer-reviewedNeuroscience