Author

Estibaliz Lopez-Rodrigo

Memorial Sloan Kettering Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Agnes J. VialeiD· 2 shared Ann Baako· 2 shared Araitz AlberdiiD· 2 shared Bertrand BoissoniD· 2 shared Christine A. Iacobuzio–DonahueiD· 2 shared Frédéric GeissmanniD· 2 shared Jean‐Laurent CasanovaiD· 2 shared Masato OgishiiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Agnes J. VialeORCID

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Author profile →

2 papers

Recent·Most cited

Mechanism of neurodegeneration mediated by clonal inflammatory microglia

Rocío Vicario, Stamatina Fragkogianni, Maria V. Pokrovskii, Carina Meyer, Estibaliz Lopez-Rodrigo, Yang Hu, Masato Ogishi, Araitz Alberdi, Ann Baako, Oyku Ay, Isabelle Plu, Véronique Sazdovitch, Sébastien Héritier, Fleur Cohen Aubart, Natalia Shor, , Frédéric Geissmann

The paper identifies clonal inflammatory microglia as a cause of neurodegeneration in LCH and ECD, showing their association with neuronal loss and suggesting CSF1R inhibitors as a therapeutic option.

Neuron · Mar 12, 2025Peer-reviewedImmunology

A microglia clonal inflammatory disorder in Alzheimer's Disease

Rocío Vicario, Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y. Hayashi, Barbara P. Craddock, Nicholas D. Socci, Araitz Alberdi, Ann Baako, Oyku Ay, Masato Ogishi, Estibaliz Lopez-Rodrigo, Rajya L. Kappagantula, Agnes J. Viale, , Frédéric Geissmann

The paper identifies microglia-specific somatic clones with pathogenic variants in Alzheimer's Disease patients that drive neuro-inflammation through the MAPK pathway.

eLife · Jan 29, 2025Peer-reviewedNeuroscience