Author

Lauren Broestl

Washington University in St. LouisORCID 0000-0002-6566-3986Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Arnav MoudgiliD· 1 shared Briana C. PrageriD· 1 shared Jason GertziD· 1 shared Jeremy N. RichiD· 1 shared Joshua B. RubiniD· 1 shared Kristopher Berrett· 1 shared Michael WilkinsoniD· 1 shared Najla KfouryiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Arnav MoudgilORCID

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1 paper

Recent·Most cited

Brd4-bound enhancers drive cell intrinsic sex differences in glioblastoma

Najla Kfoury, Zongtai Qi, Briana C. Prager, Michael Wilkinson, Lauren Broestl, Kristopher Berrett, Arnav Moudgil, Sumithra Sankararaman, Xuhua Chen, Jason Gertz, Jeremy N. Rich, Robi David Mitra, Joshua B. Rubin

This study identifies sex differences in glioblastoma driven by Brd4-bound enhancers, showing opposing responses to BET inhibitors in male and female tumor cells.

Proceedings of the National Academy of Sciences · Apr 13, 2021Peer-reviewedGenomics