Author

Sumithra Sankararaman

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Robi David MitraiD· 2 shared Aldrin Kay‐Yuen YimiD· 1 shared Arnav MoudgiliD· 1 shared Avinash RamuiD· 1 shared Briana C. PrageriD· 1 shared Christopher A. MaheriD· 1 shared Denis R. AveyiD· 1 shared Douglas R. AdkinsiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersGenomics

Robi David MitraORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

RegTools: Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer

Kelsy C. Cotto, Yang-Yang Feng, Avinash Ramu, Megan M. Richters, Sharon L. Freshour, Zachary L. Skidmore, Huiming Xia, Joshua F. McMichael, Jason Kunisaki, Katie Marie Campbell, Timothy Hung-Po Chen, Emily B. Rozycki, Douglas R. Adkins, Siddhartha H. K. Devarakonda, Sumithra Sankararaman, , Malachi Griffith

RegTools identifies splice-associated variants in cancer by integrating genomic and transcriptomic data across 9,000 tumor samples, discovering 235,778 splicing events.

Nature Communications · Mar 22, 2023Peer-reviewedBioinformatics

Brd4-bound enhancers drive cell intrinsic sex differences in glioblastoma

Najla Kfoury, Zongtai Qi, Briana C. Prager, Michael Wilkinson, Lauren Broestl, Kristopher Berrett, Arnav Moudgil, Sumithra Sankararaman, Xuhua Chen, Jason Gertz, Jeremy N. Rich, Robi David Mitra, Joshua B. Rubin

This study identifies sex differences in glioblastoma driven by Brd4-bound enhancers, showing opposing responses to BET inhibitors in male and female tumor cells.

Proceedings of the National Academy of Sciences · Apr 13, 2021Peer-reviewedGenomics

Single cell RNAseq uncovers a robust transcriptional response to morphine by oligodendrocytes

Denis R. Avey, Sumithra Sankararaman, Aldrin Kay‐Yuen Yim, Ruteja A. Barve, Robi David Mitra, Jeffrey Milbrandt

This study identifies morphine-induced gene expression changes in oligodendrocytes using single-cell RNA sequencing in mice, highlighting pathways related to myelination.

bioRxiv · Apr 24, 2018 · PreprintNeuroscience