ImmunologybioRxivPreprint
P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by Borrelia burgdorferi
Michal Caspi Tal, Paige S. Hansen, Haley A. Ogasawara…·Balyn W. Zaro
This study identifies P66, a bacterial protein mimicking CD47, which binds SIRPα to evade macrophage phagocytosis, and shows its role in Lyme Disease pathogenesis.
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