Author

Sean Patrick Murphy

University of Notre DameORCID 0000-0002-6582-4065Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Sharif RahmyiD· 2 shared Xin LüiD· 2 shared Abigail E. EllisiD· 1 shared Dailin GaniD· 1 shared Emma Albano· 1 shared James H. SchofieldiD· 1 shared Joseph LongoiD· 1 shared Jun LiiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Sharif RahmyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedMar 24, 2024

Acod1 Expression in Cancer Cells Promotes Immune Evasion through the Generation of Inhibitory Peptides

James H. Schofield, Joseph Longo, Ryan D. Sheldon…·Zachary T. Schafer

This study shows that Acod1 in cancer cells promotes immune evasion by releasing inhibitory peptides, not ITA, and that reducing Acod1 can make tumors responsive to PD-1 therapy.

18 citations

humanproteomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintAug 7, 2023

Overcome Prostate Cancer Resistance to Immune Checkpoint Therapy with Ketogenic Diet-Induced Epigenetic Reprogramming

Sean Patrick Murphy, Sharif Rahmy, Dailin Gan…·Xin Lü

This study shows that combining ketogenic diet and HDAC inhibitors with ICB therapy enhances anti-tumor effects in prostate cancer by modulating epigenetic and immune mechanisms.

4 citations

mousescRNA-seq

𝕏 PostBluesky