Author

Shuchao Ge

Sanford Burnham Prebys Medical Discovery InstituteORCID 0000-0002-6590-9050Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:Drosophila· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Georg VogleriD· 2 shared James MarchantiD· 2 shared Karen A. OcorriD· 2 shared Rolf BodmeriD· 2 shared Adam Jeffrey EngleriD· 1 shared Alexandre R. ColasiD· 1 shared Cristiana DondiiD· 1 shared Jeanne L. TheisiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Georg VoglerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Deficiency in MICOS component Chchd3 Compromises Drosophila Heart Function via mitophagy, ROS and ER Stress

Cristiana Dondi, Shuchao Ge, James Marchant, K'leigh Guillotte, Karen A. Ocorr, Georg Vogler, Rolf Bodmer

This study shows that Chchd3 deficiency in Drosophila hearts impairs function through mitophagy, ROS, and ER stress, with partial rescue by antioxidant and ER stress interventions.

bioRxiv · Aug 19, 2026 · PreprintGenetics

Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity

Katja Birker, Shuchao Ge, Natalie J. Kirkland, Jeanne L. Theis, James Marchant, Zachary C. Fogarty, Maria Azzurra Missinato, Sreehari Kalvakuri, Paul Grossfeld, Adam Jeffrey Engler, Karen A. Ocorr, Timothy J. Nelson, Alexandre R. Colas, Timothy M. Olson, Georg Vogler, Rolf Bodmer

The paper identifies mitochondrial MICOS complex genes, CHCHD3 and CHCHD6, as contributors to hypoplastic left heart syndrome through functional studies in Drosophila and genetic analysis of patient cohorts.

eLife · Jul 5, 2023Peer-reviewedGenetic & Genomic Medicine