K'leigh Guillotte

This study shows that Chchd3 deficiency in Drosophila hearts impairs function through mitophagy, ROS, and ER stress, with partial rescue by antioxidant and ER stress interventions.

The paper shows that reduced nucleosome stability impairs cell identity, stress resilience, and healthy aging across species.

The paper creates a single-cell atlas of the Drosophila embryonic heart and identifies Tinman's cell-type-specific roles in cardiac development.