Author

Yun‐Ru Chen

Genomics Research Center, Academia SinicaORCID 0000-0002-6596-6338Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Debapriya Kundu· 1 shared Lee‐Way JiniD· 1 shared Shin-Yu Fan· 1 shared Tien‐Hsien ChangiD· 1 shared Wan-Chen Lu· 1 shared Wan‐Chen HuangiD· 1 shared Wei-Wei Chang· 1 shared Wu Jp· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperNeuroscience

Debapriya Kundu

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 23, 2026

HSC70 prevents TDP-43 nuclear puncta formation and toxicity in a novel nuclear puncta cell model for ALS

Wu Jp, Shin-Yu Fan, Tien‐Hsien Chang, Yun‐Ru Chen

This paper identifies a TDP-43 mutation, G148V, that causes nuclear puncta formation and toxicity, and shows HSC70 prevents this pathology in a cellular model of ALS.

DOI 10.64898/2026.07.21.739729

humanproteomics

NeurosciencebioRxivPreprintMay 27, 2026

O-GlcNAcylation effect on Tau in modulating its seeding and cellular transmission in Alzheimer's Disease

Debapriya Kundu, Wei-Wei Chang, Wan-Chen Lu…·Yun‐Ru Chen

This study investigates how O-GlcNAcylation affects Tau aggregation and toxicity in Alzheimer's Disease, showing reduced seeding and toxicity in O-GlcNAcylated Tau.

DOI 10.64898/2026.05.27.728078

humanproteomics