Jing Guo

This paper identifies trehalose monocorynomycolate (TMCM) from C. mast as a stimulator of IL-17-producing γδ T cells at the ocular surface, which protects against corneal infection.

This study identifies Vγ6 T cells as a major C. mast-responsive subset in the conjunctiva and shows that intrinsic TLR2 signaling drives metabolic reprogramming and IL-17A production.

This study identifies cytokines that enhance influenza vaccine antibody responses in human organoids and mice, showing their potential as adjuvants to improve vaccine efficacy.

This study maps the organism-wide secretome response to exercise in mice, identifying 200+ exercise-regulated protein pairs and uncovering anti-obesity and anti-diabetic roles of a liver-secreted proteoform.