Author

Richard Thomas Amison

King's College LondonORCID 0000-0002-6616-4599Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Clive Peter PageiD· 2 shared Dingxin Pan· 2 shared Simon C. PitchfordiD· 2 shared A. E. Lino-AlvaradoiD· 1 shared Anjana SajiiD· 1 shared Claudia M. SiskiD· 1 shared Edward J. WillsiD· 1 shared Graham D. Cocks· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersPharmacology & Toxicology

Clive Peter PageORCID

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2 papers

Recent·Most cited

Discovery of a pathway-selective platelet P2Y1R inverse agonist that suppresses inflammation while preserving hemostasis

Simon C. Pitchford, Kazi Sumaita Nahar, Dingxin Pan, Claudia M. Sisk, Taha Al‐Adhami, Kubra Ekinci, Richard Thomas Amison, Nupur Gargate, Anjana Saji, Edward J. Wills, Clive Peter Page, Graham Ladds, Khondaker Miraz Rahman

This paper designs a pathway-selective P2Y1R inverse agonist that suppresses inflammation without affecting hemostasis, demonstrating its functional selectivity in vitro and in vivo.

bioRxiv · Jun 24, 2026 · PreprintPharmacology & Toxicology

Platelet-specific P2Y1 receptor deficient mice have suppressed leukocyte recruitment in response to lipopolysaccharide.

Dingxin Pan, A. E. Lino-Alvarado, Richard Thomas Amison, Tolga Oralman, Reah Evans, Oliver Keith Baker, Graham D. Cocks, Clive Peter Page, Simon C. Pitchford

This study creates a platelet-specific P2Y1 receptor knockout mouse model and shows it suppresses leukocyte recruitment during inflammation.

Respiratory Research · Mar 5, 2026Peer-reviewedPharmacology & Toxicology