Author

Kyle I. Mentkowski

Harvard UniversityORCID 0000-0002-6623-2096Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexandre PaccaletiD· 2 shared Charlotte G. MuseiD· 2 shared Hana SeungiD· 2 shared I‐Hsiu LeeiD· 2 shared Kamila NaxerovaiD· 2 shared Maarten HulsmansiD· 2 shared Matthias NahrendorfiD· 2 shared Maximilian J. SchlossiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Alexandre PaccaletORCID

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2 papers

Recent·Most cited

ImmunologyNature Cardiovascular ResearchPeer-reviewedApr 23, 2026

Therapeutic Spp1 silencing in TREM2+ cardiac macrophages suppresses atrial fibrillation

Noor Momin, Steffen Pabel, Arnab Rudra…·Maarten Hulsmans

This study shows that silencing Spp1 in TREM2+ cardiac macrophages reduces atrial fibrosis and suppresses AFib in mice, suggesting a new immunotherapy approach.

25 citationstop 1%

mouseexperimental assay

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ImmunologybioRxivPreprintMar 28, 2025

Bone marrow mesenchymal stromal cells mediate cellular inflammation in HFpEF

Kyle I. Mentkowski, I‐Hsiu Lee, David Rohde…·Matthias Nahrendorf

The paper shows that bone marrow stromal cells in HFpEF respond to IFNγ, driving monocyte expansion and fibrosis, which can be mitigated by IFNγ receptor deletion.

1 citation

mousescRNA-seq

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