Noor Momin

This study shows that silencing Spp1 in TREM2+ cardiac macrophages reduces atrial fibrosis and suppresses AFib in mice, suggesting a new immunotherapy approach.

The paper shows that bone marrow stromal cells in HFpEF respond to IFNγ, driving monocyte expansion and fibrosis, which can be mitigated by IFNγ receptor deletion.

This study evaluates collagen-binding IL-2 and IL-12 in pet dogs with melanoma, showing local and regional therapeutic responses that suggest potential human clinical benefit.