Systems BiologyPLoS Computational BiologyPeer-reviewed
Systematic computational assessment of atrial function impairment due to fibrotic remodeling in electromechanical properties
Åshild Telle, Ahmad Kassar, Nadia Chamoun…·Patrick M. Boyle
This study uses a computational model to assess how fibrosis-related changes in electrophysiological and mechanical properties affect left atrial function, finding that reduced L-type calcium current most impairs function while reduced inward rectifier current improves it.
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