Author

Nikoleta Kircheva

Bulgarian Academy of SciencesORCID 0000-0002-6645-8319Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andreas BrandstätteriD· 1 shared Bojan ŽagrovićiD· 1 shared Christoph BockiD· 1 shared David HaselbachiD· 1 shared Dorothea AnratheriD· 1 shared Egon OgrisiD· 1 shared Fran Miočić-Stošić· 1 shared Irina GrishkovskayaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Andreas BrandstätterORCID

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1 paper

Recent·Most cited

PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor

Tarik Husremović, Vanessa Meier, Lucas Piëch, Katharina M. Siess, Sumire Antonioli, Irina Grishkovskaya, Nikoleta Kircheva, Silvia Angelova, Karoline Wenzl, Andreas Brandstätter, Jiri Veis, Fran Miočić-Stošić, Dorothea Anrather, Markus Hartl, Linda Truebestein, , Thomas A. Leonard

This study reveals that PHLPP2 is a pseudophosphatase with no catalytic activity, challenges its role as a tumor suppressor, and identifies its non-catalytic functions in Akt signaling.

Proceedings of the National Academy of Sciences · Apr 1, 2025Peer-reviewedBiochemistry