Author

David Homolka

University of GenevaORCID 0000-0002-6662-3409Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:multiome· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Ramesh S. PillaiiD· 3 shared Cathrine Broberg VågbøiD· 2 shared Elena DelfinoiD· 2 shared Bettina Salome TrüebiD· 1 shared Carmen Fernández‐RodrígueziD· 1 shared Devanshi JainiD· 1 shared Fabienne Burger· 1 shared G. Tuba BarutiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Ramesh S. PillaiORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 29, 2026

Cap-specific second nucleotide ribose methylase CMTR2 is required for transcriptome transition during mammalian germline development

Harsha Raheja, Elena Delfino, Michaela Dohnálková…·Ramesh S. Pillai

This study shows that CMTR2 is essential for transcriptome transitions during mammalian germline development but does not trigger innate immune responses.

DOI 10.64898/2026.07.28.741271

mousehuman

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Molecular BiologybioRxivPreprintApr 13, 2026

Loss of host factor-mediated m6Am methylation of the viral RNA cap impairs SARS CoV-2 replication

Radha Raman Pandey, Nadine Ebert, David Homolka…·Ramesh S. Pillai

This study identifies PCIF1 as a host factor that methylates the SARS-CoV-2 RNA cap, enhancing viral replication and reducing disease severity in mice.

DOI 10.64898/2026.04.10.717462

humanmouse

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Developmental BiologyCell ReportsPeer-reviewedDec 1, 2021

YTHDC2 Is Essential for Pachytene Progression and Prevents Aberrant Microtubule-Driven Telomere Clustering in Male Meiosis

Rong Liu, Seth D. Kasowitz, David Homolka…·P. Jeremy Wang

This study shows YTHDC2 is essential for meiotic pachytene progression by maintaining a meiotic transcriptome and preventing microtubule-driven telomere clustering.

39 citationstop 2%

mousebulk RNA-seq

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