Simone Pompei

The paper quantifies mating strategies in yeast gametes, revealing a reproductive hierarchy where sibling gametes have divergent mating trajectories and temporal heterogeneity shapes compatibility.

This study uses mathematical modeling to show that optimal cancer treatment involves intermittent dosing with lower drug concentrations and recovery periods, potentially improving efficacy over continuous regimens.

The paper measures mutation rates in microsatellite stable colorectal cancers and finds they vary between tumors and increase during metastasis.

This paper introduces μSeq, a method for accurately quantifying mutation rates using deep sequencing of single clonal expansions, showing it outperforms existing methods in robustness and accuracy.