Author

Kwok-Ho Chan

GlaxoSmithKline (United Kingdom)ORCID 0000-0002-6693-2682Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Agnieszka KonopackaiD· 1 shared Gopal P. SapkotaiD· 1 shared Houjiang ZhouiD· 1 shared Markus A. QueisseriD· 1 shared Sascha RöthiD· 1 shared Thomas MacartneyiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Agnieszka KonopackaORCID

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1 paper

Recent·Most cited

Molecular BiologyCell chemical biologyPeer-reviewedJul 14, 2020

Targeting endogenous K-RAS for degradation through the affinity-directed protein missile system

Sascha Röth, Thomas Macartney, Agnieszka Konopacka…·Gopal P. Sapkota

This paper demonstrates the degradation of endogenous K-RAS and H-RAS using an AdPROM system, offering a new approach for targeting undruggable cancer proteins.

64 citations

humanexperimental assay

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