Author

Philipp Heher

King's College LondonORCID 0000-0002-6722-5875Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Peter S. ZammitiD· 2 shared Christopher R. S. BanerjiiD· 1 shared Elise N. EngquistiD· 1 shared Giorgio A. TascaiD· 1 shared Jakob Pfeiffer-VogliD· 1 shared Jiani Qian· 1 shared Johanna PrülleriD· 1 shared Johannes GrillariiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Peter S. ZammitORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Metformin enhances differentiation and function of skeletal muscle in models of Facioscapulohumeral Muscular Dystrophy (FSHD)

Joshua Greig, Jiani Qian, Philipp Heher, Peter S. Zammit

This study shows that Metformin improves muscle differentiation and function in FSHD models by reducing oxidative stress and enhancing metabolic health.

bioRxiv · Jul 31, 2026 · PreprintCell Biology

Mitochondrial Respiratory Chain Function is crucial for Muscle Toxicity in Facioscapulohumeral Muscular Dystrophy

Philipp Heher, Jakob Pfeiffer-Vogl, Massimo Ganassi, Raul-Cristian Fulea, Liam McGuire, Elise N. Engquist, M Tyszkiewicz, Johanna Prüller, Johannes Grillari, Giorgio A. Tasca, Christopher R. S. Banerji, Peter S. Zammit

This study identifies mitochondrial respiratory chain dysfunction and reverse electron transfer as key drivers of DUX4-induced toxicity in FSHD, suggesting RET inhibition as a therapeutic target.

bioRxiv · Nov 25, 2025 · PreprintBiochemistry