Massimo Ganassi

This study identifies mitochondrial respiratory chain dysfunction and reverse electron transfer as key drivers of DUX4-induced toxicity in FSHD, suggesting RET inhibition as a therapeutic target.

This study shows that Piezo1 regulates myocyte fusion during skeletal myogenesis by modulating Ca2+ influx and Myomaker expression, with implications for muscle diseases.

This study shows that Myogenin regulates adult muscle fibre growth and stem cell homeostasis by affecting myonuclear domain size, MuSC activation, and mTORC1 signaling.