Author

Henrik Semb

Helmholtz MunichORCID 0000-0002-6747-787XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Abigail Laura JacksoniD· 1 shared Anahita Soltanian· 1 shared Anant MamidiiD· 1 shared Anders H. RosengreniD· 1 shared Christine EbeidiD· 1 shared Fiona Louise RobertsiD· 1 shared Hindrik MulderiD· 1 shared Jelena Miskovic KrivokapiciD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Abigail Laura JacksonORCID

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2 papers

Recent·Most cited

Modelling genetic risk of β-cell dysfunction in human induced pluripotent stem cells from patients carrying the MTNR1B risk variant.

T. Singh, Sebastian Kalamajski, João Gabriel Dantas Cunha, Siarhei Hladkou, Fiona Louise Roberts, Sevda Gheibi, Anahita Soltanian, K. Yektay Farahmand, Ola Ekström, Anant Mamidi, Paul W. Franks, Anders H. Rosengren, Henrik Semb, Hindrik Mulder, Malin Fex

This study uses hiPSC and hESC to model the MTNR1B risk variant's effect on β-cell function, finding increased MTNR1B protein and melatonin sensitivity in G-allele carriers.

Journal of Pineal Research · Sep 1, 2025Peer-reviewedCell Biology

Real time quantification reveals novel dynamic processes in pancreatic lumenal network establishment and remodeling

Abigail Laura Jackson, Silja Heilmann, Christine Ebeid, Jelena Miskovic Krivokapic, José Alejandro Romero Herrera, Henrik Semb, Pia Nyeng

The paper uses real-time imaging to reveal dynamic processes in pancreatic lumen formation and remodeling, challenging existing models of polarity acquisition and network development.

bioRxiv · Aug 18, 2023 · PreprintDevelopmental Biology