The paper develops a polymer micelle model to explain how enhancer-promoter conformation and micelle stability influence transcriptional bursting kinetics.

bioRxiv · May 2, 2026 · PreprintBiophysics

Reorganization of DNA loops by competition between condensin I and a linker histone

Tetsuya Yamamoto, Keishi Shintomi, Tatsuya Hirano

The paper investigates how condensin I and linker histone H1.8 compete to reorganize DNA loops in a sparkler structure formed in Xenopus egg extracts.

Biophysical Journal · Sep 24, 2025Peer-reviewedBiophysics

Mental Effort Cost Learning is Retrospective

Asako Mitsuto Nagase, Rei Akaishi, Keiichi Onoda, Kenji Morita, Toshikazu Kawagoe, Tetsuya Yamamoto, Shuhei Yamaguchi, Ritsuko Hanajima, Andrew Westbrook

This study shows mental effort cost learning is retrospective, updating decisions based on prediction errors at effort completion, not during the task.

bioRxiv · Nov 26, 2022 · PreprintNeuroscience

Paraspeckles are constructed as block copolymer micelles through microphase separation

Tomohiro Yamazaki, Tetsuya Yamamoto, Hyura Yoshino, Sylvie Souquère, Shinichi Nakagawa, Gérard Pierron, Tetsuro Hirose

This paper investigates how paraspeckles form through microphase separation, showing they behave like block copolymer micelles.

bioRxiv · Nov 2, 2020 · PreprintMolecular Biology