Takashi Fukaya

The paper develops a polymer micelle model to explain how enhancer-promoter conformation and micelle stability influence transcriptional bursting kinetics.

The paper shows that Shutdown's transient presence in Yb bodies is crucial for Piwi-piRISC formation and fertility, mediated by its self-repulsion and interaction with Armitage.

This study investigates ZAD-ZnF transcription factors in Drosophila, showing they form nuclear condensates and interact with insulator proteins, highlighting their role in development and genome organization.

This study identifies Mulberry as a looping factor in Drosophila embryos that shapes genome organization through nuclear condensates and long-range regulatory interactions.

APEX-Ribo-Seq maps local translation across organelles and identifies compartment-specific transcripts, revealing sequence features and dynamics of subcellular translation.

This study uses live-imaging in Drosophila to show that enhancer transcription suppresses gene transcriptional bursting and affects transcription hub formation during development.

The paper shows Mod(mdg4)-N variants repress HeT-A retrotransposons by blocking subtelomeric enhancers in Drosophila ovarian cells, leading to female sterility.

The paper shows core promoter elements dynamically modulate enhancer responsiveness in Drosophila embryos by altering transcriptional bursting parameters.

This study investigates how transcriptional bursting and enhancer interactions regulate gene expression patterns in Drosophila embryos.