An efficient behavioral screening platform classifies natural products and other chemical cues according to their chemosensory valence in C. elegans
Emily Fryer, Sujay Guha, Lucero E. Rogel-Hernandez, Theresa Logan-Garbisch, Hodan Farah, Ehsan Rezaei, Iris Natalie Mollhoff, Adam L. Nekimken, Angela Xu, Lara Selin Seyahi, Sylvia Fechner, Shaul Druckmann, Thomas R. Clandinin, Seung Y. Rhee, Miriam B. Goodman
The paper introduces a platform to classify chemical cues by their chemosensory valence in C. elegans, identifying 37 plant small molecules that attract or repel wild-type worms.
bioRxiv · Jun 2, 2023 · PreprintNeuroscience