Author

Rakesh Roy

Ollscoil na Gaillimhe – University of GalwayORCID 0000-0002-6809-0431Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Donald R. RonningiD· 1 shared James P. O’GaraiD· 1 shared Merve Suzan ZedeniD· 1 shared Sasmita Panda· 1 shared Vinai Chittezham ThomasiD· 1 shared Yahani P. JayasingheiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

Donald R. RonningORCID

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1 paper

Recent·Most cited

A D-alanine aminotransferase S180F substitution confers resistance to β-chloro-D-alanine in Staphylococcus aureus via antibiotic inactivation

Rakesh Roy, Yahani P. Jayasinghe, Sasmita Panda, Merve Suzan Zeden, Vinai Chittezham Thomas, Donald R. Ronning, James P. O’Gara

This study identifies a S180F substitution in D-alanine aminotransferase (Dat) in Staphylococcus aureus that confers resistance to β-chloro-D-alanine by altering PLP co-factor binding and promoting antibiotic inactivation.

bioRxiv · Aug 17, 2025 · PreprintMicrobiology