Yoshikazu Johmura

This study shows that STING inhibits microglial phagocytosis and protects neurons during epileptogenesis by regulating calcium signaling through the STING-STIM1-SOCE axis.

This study uses single-cell RNA sequencing to show that the GLS1 inhibitor BPTES eliminates inflammatory senescent cells in aged mice and reduces chronic inflammation.

This study identifies FBXO22 deficiency as a cause of a pleiotropic syndrome with growth restriction and neurodevelopmental delay, linked to an epigenetic signature involving histone demethylase KDM4B.