Kinichi Nakashima

This study shows that STING inhibits microglial phagocytosis and protects neurons during epileptogenesis by regulating calcium signaling through the STING-STIM1-SOCE axis.

This study shows that blocking ADGRG1 allows astrocytes to enter the fibrotic matrix, reducing scar size and improving motor recovery after CNS injury.

This study identifies Gelsolin as a regulator of ER stress in psoriasis-like dermatitis, showing it counteracts inflammatory circuits driven by IMQ-induced organelle stress.

The paper shows that spaceflight triggers neural senescence via reactivation of dormant viral-like retroelements, and that reverse transcriptase inhibitors can reverse these effects.

This study shows that KIT-13, a plasmalogen derivative, reduces neuroinflammation and improves mitochondrial function in a mouse model of Rett syndrome, leading to better neurological outcomes.

This study identifies the MeCP2/miR-199a/Qki axis as critical for dendritic development and shows its dysregulation contributes to dendritic pathology in Rett syndrome.

This study converts microglia/macrophages into neurons in the injured brain to restore neurological function after stroke.

This study shows that Derlin-1 maintains adult neurogenesis by regulating Stat5b, thereby affecting seizure susceptibility and cognitive function in mice.

This study shows that high NeuroD1 expression or its combination with other reprogramming factors improves neuronal conversion efficiency from glial cells.

The paper identifies a TCF-4-dependent transcription factor network regulating commissure development in mice using scRNA-seq and bioinformatic analysis.

This study shows that Sufu regulates Shh signaling to control the expansion and quiescence of neural stem cells in the developing dentate gyrus.