Dazhuan Eric Xin

This study uses single-cell and spatial omics to identify plasticity and therapeutic targets in metastatic high-risk neuroblastoma.

This study identifies tonic signaling as a key factor in CAR-T cell efficacy for diffuse midline glioma, showing that restrained tonic signaling improves therapeutic outcomes.

The paper validates the existence of transitional cerebellar progenitors using multimodal approaches across multiple datasets and stages.

This study shows that Tet1-mediated DNA hydroxymethylation is essential for myelination and remyelination in mice by regulating oligodendrocyte differentiation and calcium signaling.