Author

Charles B. Stevenson

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-9375-2118Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Natasha Pillay‐SmileyiD· 2 shared Peter M K de BlankiD· 2 shared Trent Ryan HummeliD· 2 shared Abby GrieriD· 1 shared Ali TavassoliiD· 1 shared Angelo D’AlessandroiD· 1 shared Arman Esshaghi BayatiD· 1 shared Arzu Onar-Thomas· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Natasha Pillay‐SmileyORCID

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3 papers

Recent·Most cited

hTERT Expression, Regulation, and Prognostic Significance in Pediatric Medulloblastoma

Ryuma Tanaka, Banlanjo Abdulaziz Umaru, Matthew Sobo, Shiva Senthil Kumar, Kathleen McCarthy O'Toole Dorris, Volker Hovestadt, Vijay Ramaswamy, Marc Remke, Ashley Margol, Charles B. Stevenson, Shahab Asgharzadeh, Stewart Goldman, Lili Miles, Jie Huang, Katja von Hoff, , Rachid Drissi

This study examines hTERT expression and its prognostic impact in pediatric medulloblastoma, finding higher expression correlates with worse survival outcomes.

bioRxiv · May 6, 2026 · PreprintCancer Biology

A Tonic Signaling Code Predicts CAR-T Cell Efficacy in Diffuse Midline Glioma

Emily Deng, Xiaowen Zhong, Dazhuan Eric Xin, Upendra Kumar Soni, Wenkun Ma, Xiao Huang, Mingjun Cai, Po-Yu Liang, Jun Bai, Qian Qin, Shreya V. Mishra, Ming Hu, Arman Esshaghi Bayat, Jiajie Diao, Mei Xin, , Q. Richard Lu

This study identifies tonic signaling as a key factor in CAR-T cell efficacy for diffuse midline glioma, showing that restrained tonic signaling improves therapeutic outcomes.

bioRxiv · Sep 29, 2025 · PreprintCancer Biology

Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG

Ian Mersich, Sunny Congrove, Matthew J. Horchar, Román Cáceres, Ranjithmenon Muraleedharan, Janki M. Desai, Pankaj B. Desai, Larry Sallans, Julie A. Reisz, Abby Grier, Matthew R. Hass, Omer Donmez, Cailing Yin, Matthew T. Weirauch, Leah Claire Kottyan, , Biplab Dasgupta

This study identifies nuclear factor I (NFI) as a driver of dysregulated purine metabolism in DIPG, showing that targeting ATIC reduces tumor progression in mice.

bioRxiv · May 21, 2025 · PreprintCancer Biology