Systems BiologyMolecular Systems BiologyPeer-reviewed
Turnover and replication analysis by isotope labeling (TRAIL) reveals the influence of tissue context on protein and organelle lifetimes
John Hasper, Kevin A. Welle, Jennifer R. Hryhorenko…·Abigail L. Buchwalter
TRAIL quantifies protein and cell lifetimes across tissues, showing cell division drives non-selective turnover in proliferative tissues while physicochemical features influence turnover in non-proliferative tissues.
13 citations