Molecular BiologybioRxivPreprint
NRF2 pathway activation reverts high-glucose-induced transcriptional memory in endothelial cells
Martí Wilson-Verdugo, Brandon Bustos-García, Olga Adame-Guerrero…·Víctor Julián Valdés
This study shows that transient high glucose exposure induces persistent transcriptional and chromatin changes in endothelial cells, which can be reversed by NRF2 pathway activation.
DOI 10.1101/2023.09.11.557207