Maribel Soto-Nava

The paper identifies PRC2 nucleation sites in mESCs after Suz12 reintroduction, revealing chromatin states, DNA sequences, cofactors, and spatial interactions involved in de novo Polycomb recruitment.

The paper uses metabolomics to show that HIV-treated individuals have metabolic disruptions, including lipid changes and inflammation markers, despite viral suppression.

This study identifies a core gene program underlying Tfh cell differentiation using a multi-scale network systems approach, revealing a novel role for IL-12 in regulating Tfh precursor differentiation.

This study links microbial dysbiosis, systemic inflammation, and metabolomic disruptions to SNAE risk in treated HIV patients through multi-omic analysis.

The paper compares phenotypic and transcriptomic differences between a tropical wild C. elegans strain, the N2 Ancestral strain, and the domesticated N2 Bristol strain, revealing regulatory divergence due to domestication.

This study shows that transient high glucose exposure induces persistent transcriptional and chromatin changes in endothelial cells, which can be reversed by NRF2 pathway activation.