Víctor Julián Valdés

The paper identifies PRC2 nucleation sites in mESCs after Suz12 reintroduction, revealing chromatin states, DNA sequences, cofactors, and spatial interactions involved in de novo Polycomb recruitment.

This study shows that TIF1γ maintains T regulatory cell stability and suppressor function during inflammation by regulating Foxp3 expression and the beta-catenin pathway.

The paper compares phenotypic and transcriptomic differences between a tropical wild C. elegans strain, the N2 Ancestral strain, and the domesticated N2 Bristol strain, revealing regulatory divergence due to domestication.

This study shows that transient high glucose exposure induces persistent transcriptional and chromatin changes in endothelial cells, which can be reversed by NRF2 pathway activation.