Author

Reena Sarah Jacob

Manipal Academy of Higher EducationORCID 0000-0002-6834-8076Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

R.V. OmkumariD· 2 shared Ayyiliath Meleveetil SajithiD· 1 shared Chandran RemyaiD· 1 shared Chittalakkottu SadasivaniD· 1 shared E. Jayadevi VariyariD· 1 shared Eeda Koti ReddyiD· 1 shared Kalarickal Vijayan DileepiD· 1 shared Kam Y. J. ZhangiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

R.V. OmkumarORCID

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2 papers

Recent·Most cited

Novel microRNAs targeting NMDA receptor subunits in animal models of schizophrenia

Sowmya Gunasekaran, Reena Sarah Jacob, R.V. Omkumar

The paper identifies miRNAs that target NMDA receptor subunits in schizophrenia models, showing their potential role in receptor downregulation and disease mechanisms.

bioRxiv · Oct 4, 2021 · PreprintNeuroscience

Neuroprotective derivatives of tacrine that target NMDA receptor and acetyl cholinesterase - Design, synthesis and biological evaluation

Chandran Remya, Kalarickal Vijayan Dileep, Eeda Koti Reddy, Kumar Mantosh, Lakshmi Kesavan, Reena Sarah Jacob, Ayyiliath Meleveetil Sajith, E. Jayadevi Variyar, Shaik Anwar, Kam Y. J. Zhang, Chittalakkottu Sadasivan, R.V. Omkumar

The paper designs, synthesizes, and evaluates neuroprotective derivatives of tacrine that target both acetylcholinesterase and NMDA receptors, showing reduced hepatotoxicity and potential therapeutic benefits.

Computational and Structural Biotechnology Journal · Jan 1, 2021Peer-reviewedNeuroscience