Author

Sowmya Gunasekaran

Manipal Academy of Higher Education

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:rat· 1

Frequent Co-Authors

Dorit Ron AiD· 2 shared Khanhky Phamluong· 2 shared R.V. OmkumariD· 2 shared Yann EhingeriD· 2 shared Alexandra SalviiD· 1 shared Drishti SonejaiD· 1 shared Jeffrey J. MoffatiD· 1 shared Joshua D. Epstein· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersNeuroscience

Dorit Ron AORCID

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Author profile →

4 papers

Recent·Most cited

BDNF in Ventrolateral Orbitofrontal Cortex to Dorsolateral Striatum Circuit Moderates Alcohol Consumption and Gates Alcohol Habit

Sowmya Gunasekaran, Jeffrey J. Moffat, Joshua D. Epstein, Khanhky Phamluong, Yann Ehinger, Dorit Ron A

This study shows that BDNF in vlOFC-to-DLS neurons reduces alcohol intake by decreasing habitual seeking, but not sucrose intake.

bioRxiv · Jan 9, 2025 · PreprintNeuroscience

Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Mice Consuming Alcohol Attenuates Glycolysis

Yann Ehinger, Sophie Laguesse, Khanhky Phamluong, Alexandra Salvi, Yoshitaka J. Sei, Zachary W. Hoisington, Drishti Soneja, Sowmya Gunasekaran, Ken Nakamura, Dorit Ron A

The paper shows that mTORC1 activation in the nucleus accumbens of alcohol-consuming mice represses glycolysis via miR-34a-5p-mediated translation repression of Aldolase A, leading to reduced L-lactate and decreased alcohol intake.

bioRxiv · Nov 29, 2023 · PreprintNeuroscience

miR-146a and miR-200b alter cognition by targeting NMDA receptor subunits

Sowmya Gunasekaran, R.V. Omkumar

This study shows miR-146a and miR-200b target NMDA receptor subunits, altering cognition and protein levels in rat hippocampus.

iScience · Nov 5, 2022Peer-reviewedNeuroscience

Novel microRNAs targeting NMDA receptor subunits in animal models of schizophrenia

Sowmya Gunasekaran, Reena Sarah Jacob, R.V. Omkumar

The paper identifies miRNAs that target NMDA receptor subunits in schizophrenia models, showing their potential role in receptor downregulation and disease mechanisms.

bioRxiv · Oct 4, 2021 · PreprintNeuroscience