Niels Bradshaw

This study shows SpoIIE modulates cytokinesis machinery in B. subtilis to drive asymmetric cell division by interacting with MinCD and DivIB, and regulating FtsZ filament length.

The paper identifies dual-action kinase inhibitors that block the active site and enhance p38α dephosphorylation by stabilizing an accessible activation loop conformation.

The paper identifies a coiled-coil linker mechanism in RsbU that activates the General Stress Response in bacteria by transducing signals from sensor domains.

The paper identifies a conserved substrate docking interface in PPM phosphatases that determines substrate specificity through allosteric regulation.