Adaptation of endothelial cells to microenvironment topographical cues through lysyl oxidase like-2-mediated basement membrane scaffolding
Marion F. Marchand, Noémie Brassard-Jollive, Claire Leclech, Jorge Barrasa Fano, Yoann Atlas, Claudia Umaña-Diaz, Apeksha Shapeti, Corinne Ardidie‐Robouant, Tristan Piolot, Sabrina Martín, Philippe Mailly, Christophe Guilluy, Abdul I. Barakat, Catherine Monnot, Hans Van Oosterwyck, , Laurent Muller
This study shows LOXL2 mediates BM assembly in response to microenvironment topography, affecting endothelial cell behavior and barrier properties.
bioRxiv · Sep 12, 2025 · PreprintCell Biology