Author

Arielle J. D. Hay

Colorado State UniversityORCID 0000-0003-4852-560XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Julie A. MorenoiD· 2 shared Payton M. Shirley· 2 shared Amanda S. LathamiD· 1 shared Amelia D. Hines· 1 shared Anushree ChatterjeeiD· 1 shared Eric M. NicholsoniD· 1 shared Genova Mumford· 1 shared Grace M. WeismaniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Julie A. MorenoORCID

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2 papers

Recent·Most cited

Molecular BiologyPLoS PathogensPeer-reviewedJun 18, 2025

Microglia-specific NF-κB signaling is a critical regulator of prion-induced glial inflammation and neuronal loss

Arielle J. D. Hay, Katriana A. Popichak, Genova Mumford…·Julie A. Moreno

This study shows that microglial NF-κB signaling is critical for prion disease progression, with IKK KO microglia leading to faster disease onset and neuronal loss.

11 citations

mouseexperimental assay

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NeuroscienceACS Chemical NeurosciencePeer-reviewedMar 20, 2024

Targeting neuroinflammation by pharmacologic down-regulation of inflammatory pathways is neuroprotective in protein misfolding disorders.

Sydney J. Risen, Sean W. Boland, Sadhana Sharma…·Julie A. Moreno

This paper shows that targeting neuroinflammation by down-regulating NF-κB and NLRP3 with SB_NI_112 protects against neurodegeneration in prion disease models.

29 citationstop 5%

mouseexperimental assay

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