Author

Bruno Pierre Guiard

Centre National de la Recherche ScientifiqueORCID 0000-0002-6873-9966Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alejandro Orrico‐SáncheziD· 1 shared Angelo PariniiD· 1 shared Antoine PaccardiD· 1 shared Barbara BournetiD· 1 shared Bruno J. VellasiD· 1 shared Carole Gruszczynski· 1 shared Catalina BetancuriD· 1 shared Céline DeraisoniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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1 shared paperNeuroscience

Alejandro Orrico‐SánchezORCID

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2 papers

Recent·Most cited

Pathogenicity of Commensal Gut Biofilm In Prefrail Aging

Guillaume Le Cosquer, Melissa Pannier, Elodie Servanne-Meunier, Julie Thevenin, Elise Pyhourquet, Sophie Guyonnet, Bruno J. Vellas, Yohan Santin, Bruno Pierre Guiard, Angelo Parini, Louis Buscail, Barbara Bournet, Damien Guillemet, Céline Deraison, Nathalie Vergnolle, , for the IHU HealthAge INSPIRE/Open Science study group

The paper investigates prefrail gut microbiota biofilm changes and their inflammatory effects, showing potential for microbiota-targeted interventions in aging.

npj Biofilms and Microbiomes · May 22, 2025Peer-reviewedMicrobiology

Organic cation transporter 2 contributes to SSRI antidepressant efficacy by controlling tryptophan availability in the brain

Alejandro Orrico‐Sánchez, Bruno Pierre Guiard, Stella Manta, Jacques Callebert, Jean‐Marie Launay, Franck Louis, Antoine Paccard, Carole Gruszczynski, Catalina Betancur, Vincent Vialou, Sophie Gautron

This study shows OCT2 regulates tryptophan availability in the brain, affecting SSRI efficacy in a depression model.

Translational Psychiatry · Sep 29, 2023Peer-reviewedNeuroscience