Louise Ryan

A comparative genomics framework for identifying historical population bottlenecks using olfactory receptor gene evolution

The paper introduces a metric called DLR to identify population bottlenecks by analyzing olfactory receptor gene evolution across multiple mammalian species.

Expansion of Olfactory Receptor Family 14 Across Fossorial and Insectivorous Mammals

The paper identifies OR14 gene family expansion in fossorial and insectivorous mammals, linking it to ecological adaptation and convergent evolution.

GENE-FAM: An automated pipeline for mining gene families and its application to MADS-box genes in Cannabis sativa

GENE-FAM is an automated pipeline for gene family mining applied to MADS-box genes in Cannabis sativa, identifying conserved and divergent subfamilies across species.

Integrating gene annotation with orthology inference at scale

TOGA integrates gene annotation and orthology inference across hundreds of genomes, improving ortholog detection and creating large comparative gene resources.

Relating enhancer genetic variation across mammals to complex phenotypes using machine learning

A machine learning approach identifies enhancer-phenotype associations across mammals, revealing links to brain size and behavior evolution.

Insights into mammalian TE diversity via the curation of 248 mammalian genome assemblies

The paper curates TE content in 248 mammalian genomes, finding trends in recent TE accumulation and associations with dietary habits.

Evolutionary constraint and innovation across hundreds of placental mammals

A 240-species placental mammal alignment resolves constraint to single bases, estimating at least 10.7% of the human genome is constrained, with 48.5% of constrained bases unannotated.

Chiropterans are a hotspot for horizontal transfer of DNA transposons in Mammalia

The paper identifies bats as a hotspot for horizontal transfer of DNA transposons, finding over 200 putative elements and shared transposons across mammals and reptiles.