The paper investigates how infauna affect DNA and RNA virus communities in marine sediments, finding increased DNA virus abundance and activity under higher infauna conditions.

bioRxiv · Mar 18, 2026 · PreprintMicrobiology

Viral challenges and adaptations between Central Arctic Ocean and atmosphere

Janina Rahlff, George Westmeijer, Julia Weißenbach, Alfred A. Antson, Karin Holmfeldt

The paper studies viral diversity and adaptations in Central Arctic Ocean and atmosphere, finding that viruses use strategies to survive in extreme environments and that the air-sea interface plays a role in viral distribution.

Microbiome · Oct 24, 2024Peer-reviewedMicrobiology

Four additional natural 7-deazaguanine derivatives in phages and how to make them

Cui Liang, Seetharamsing Balamkundu, Chuan‐Fa Liu, Hong Ye, Jacob Hourihan, Astrid Rausch, Christopher Hauß, Emelie Nilsson, Matthias Hoetzinger, Karin Holmfeldt, Weijia Zhang, Laura Martínez-Álvarez, Xu Peng, Denise M. Tremblay, Sylvain Moineau, , Geoffrey Hutinet

The paper identifies four new 7-deazaguanine derivatives in phages and characterizes enzymes involved in their biosynthesis and insertion into DNA.

Nucleic Acids Research · Aug 7, 2023Peer-reviewedGenomics

Structure and function of virion RNA polymerase of crAss-like phage

Arina V. Drobysheva, Софья Андреевна Панафидина, Matvey V. Kolesnik, Evgeny I. Klimuk, Минахин Леонид Станиславович, Maria V. Yakunina, Sergei I. Borukhov, Emelie Nilsson, Karin Holmfeldt, Natalya Yutin, Kira S. Makarova, Eugene V. Koonin, Konstantin Severinov, P.G. Leiman, Maria L. Sokolova

The paper characterizes the structure and function of a novel DNA-dependent RNA polymerase from a crAss-like phage, showing its role in phage gene transcription and structural similarity to eukaryotic RNA interference polymerases.

Nature · Nov 18, 2020Peer-reviewedMolecular Biology