Author

Xiaozhong Peng

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0002-9592-9554Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Boqin Qiang· 2 shared Pengcheng ShuiD· 2 shared Shuaiyao LuiD· 2 shared A. R. S. BlackiD· 1 shared Ajitha RajaniD· 1 shared Alan SerrelsiD· 1 shared Alexander E.P. LoftusiD· 1 shared Bin YiniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersDevelopmental Biology

Boqin Qiang

Mutual co-authors in cluster

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4 papers

Recent·Most cited

FAK inhibitor treatment systemically regulates the glioblastoma immune environment via blocking monocyte trafficking

Emily R. Webb, A. R. S. Black, Giovana Carrasco, Muhammad Furqan, Robert L. Hollis, Alexander E.P. Loftus, Joel A Ochoa, Romain Enjalbert, Tara Best, Xiaozhong Peng, Morwenna Muir, Fraser Laing, Martin W. Lee, Sofian Al Shboul, Tongjie Wang, , Valerie G. Brunton

This study shows that systemic FAK inhibition reduces immunosuppressive macrophages in glioblastoma by blocking monocyte trafficking, enhancing T cell activity and improving survival in a mouse model.

bioRxiv · Nov 26, 2025 · PreprintImmunology

Temporal transcriptomic dynamics in developing macaque neocortex

Longjiang Xu, Zan Yuan, Jiafeng Zhou, Yuan Zhao, Wei Yong Liu, Shuaiyao Lu, Zhanlong He, Boqin Qiang, Pengcheng Shu, Yang Chen, Xiaozhong Peng

This study maps the temporal transcriptomic changes in rhesus macaque neocortex during neurogenesis, revealing distinct lineage trajectories and signaling pathway divergence.

eLife · Sep 25, 2023Peer-reviewedDevelopmental Biology

Comprehensive analysis of RNA-seq and whole genome sequencing data reveals no evidence for SARS-CoV-2 integrating into host genome

Yusheng Chen, Shuaiyao Lu, Bing Zhang, Tingfu Du, Wenjie Li, Lei Meng, Yanan Zhou, Yong Zhang, Penghui Liu, Yongqiao Sun, Yongliang Zhao, Ying Yang, Xiaozhong Peng, Yun‐Gui Yang

The paper analyzes RNA-seq and whole genome sequencing data from SARS-CoV-2 infected cells to determine if the virus integrates into the host genome, finding no evidence of integration.

Protein & Cell · Aug 2, 2021Peer-reviewedGenomics

COMPASS Family Histone Methyltransferase ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signalling

Liang Li, Xiangbin Ruan, Chang Wen, Pan Chen, Wei Liu, Liyuan Zhu, Pan Xiang, Xiaoling Zhang, Qunfang Wei, Lin Hou, Bin Yin, Jiangang Yuan, Boqin Qiang, Pengcheng Shu, Xiaozhong Peng

This study shows that ASH2L regulates Wnt-β-catenin signalling in NPCs, affecting their proliferation and neuronal positioning during corticogenesis.

Cell Reports · Jul 1, 2019Peer-reviewedNeuroscience