Author

Shalni Kumar

University of California San DiegoORCID 0000-0002-6903-2559Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Jeff HastyiD· 2 shared Andrew LeziaiD· 1 shared Daniel L. WorthleyiD· 1 shared Elaine M. ThomasiD· 1 shared Feargal J. RyaniD· 1 shared Georgette RadfordiD· 1 shared Jarrad M. Goyne· 1 shared Jia Q. NgiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersSynthetic Biology

Jeff HastyORCID

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2 papers

Recent·Most cited

Engineered bacteria detect tumor DNA

Robert M. Cooper, Josephine A. Wright, Jia Q. Ng, Jarrad M. Goyne, Nobumi Suzuki, Young-Kyung Lee, Mari Ichinose, Georgette Radford, Feargal J. Ryan, Shalni Kumar, Elaine M. Thomas, Laura Vrbanac, Rob D. Knight, Susan Lesley Woods, Daniel L. Worthley, Jeff Hasty

This paper engineers bacteria to detect tumor DNA through horizontal gene transfer, achieving 100% discrimination between mice with and without colorectal cancer.

Science · Aug 10, 2023Peer-reviewedSynthetic Biology

Exploiting heterogeneity in coupled, two plasmid systems for dynamic population adaptation

Shalni Kumar, Andrew Lezia, Jeff Hasty

This study shows that using plasmids with identical origins of replication in synthetic bacterial systems can enable population adaptation through copy number coupling and memory.

bioRxiv · Feb 19, 2023 · PreprintSynthetic Biology