Engineered bacteria detect tumor DNA
Robert M. Cooper, Josephine A. Wright, Jia Q. Ng, Jarrad M. Goyne, Nobumi Suzuki, Young-Kyung Lee, Mari Ichinose, Georgette Radford, Feargal J. Ryan, Shalni Kumar, Elaine M. Thomas, Laura Vrbanac, Rob D. Knight, Susan Lesley Woods, Daniel L. Worthley, Jeff Hasty
This paper engineers bacteria to detect tumor DNA through horizontal gene transfer, achieving 100% discrimination between mice with and without colorectal cancer.
Science · Aug 10, 2023Peer-reviewedSynthetic Biology